How It Works
14 articles with genetic insights and evidence-tiered analysis.
Does Selank Increase BDNF? How the Russian Anxiety Peptide Actually Repairs Your Brain
Does selank increase BDNF? It does, but not directly. Selank removes the cortisol block on your brain repair system. BDNF variants relate to how that signal is carried.
How to Read Peptide Bloodwork: 7 Numbers That Actually Matter
What blood tests do you need for peptides? Beyond IGF-1, six more numbers tell you if your GH, healing, or fat-loss protocol is working or quietly going wrong.
The IGF-1 to IGFBP-3 Ratio Explained: What It Actually Tells You About Your Peptide Protocol
Low IGFBP-3 means more free IGF-1 than your blood test implies. What the IGF-1:IGFBP-3 molar ratio tells you on GH peptide protocols, and what a skewed value signals.
When to Take Ipamorelin: Pre-Sleep, Morning, and Post-Workout Protocols Compared
When to take ipamorelin? The real variable is fasting state, not bedtime. Post-meal dosing loses 40-70% of GH pulse amplitude to somatostatin. Here is the complete protocol guide.
Why Intranasal Peptides Reach the Brain Faster Than Injection: The Olfactory Route Explained
Intranasal peptide absorption via the olfactory nerve bypasses the BBB. Studies show up to 20x more brain delivery than injection, depending on where the spray actually lands.
7 Signs Your Peptide Protocol Is Working (And 3 Signs It Is Not)
How do you know if peptides are working? Sleep changes by day 14, IGF-1 at week 6. Seven confirmed signals, 3 red flags, and why your genetics change the timeline.
How Long Does It Actually Take for GH Receptors to Reset After a Peptide Cycle? (Week by Week)
How long off GH peptides before restarting? Research shows 21-28 days minimum, but which peptide you ran and your receptor genetics changes the exact number.
Why Leaky Gut Destroys Your Liver (And How BPC-157 and GLP-2 Stop the Damage)
Leaky gut sends bacterial toxins straight to your liver via the portal vein. BPC-157 and GLP-2 stop the damage at the source, and how sensitive your toxin alarm is decides how hard each hit lands.
Oral Peptide Bioavailability: Less Than 1% Makes It Out Alive
Can you take peptides orally? Yes. But almost none of an oral dose reaches your blood. The bioavailability data by route, and what it changes in your protocol.
Ipamorelin Before Bed: How Your Circadian Genes Determine Whether It Improves Your Sleep
Does ipamorelin actually improve sleep, or just growth hormone? A 2022 study inverted the answer. How deep and how late your own body clock runs decides who feels anything.
How to Read Your Peptide DNA Report: 9 Sections, Plain English
Your peptide DNA report has 9 sections that most people skim past. Here is what each one is actually telling you, the mistakes readers make, and how to turn a score into a protocol.
Why GHK-Cu Works for Some People and Not Others: The Real Reason
Why doesn't GHK-Cu work for everyone? Three factors shape the outcome: serum concentration, age-related collagen deficit, and your skin genetics.
7 Things to Know Before Your First Peptide Therapy Appointment
First peptide therapy appointment? Most clinics skip labs, legal checks, and the genetic step that changes everything. Here is the 7-point checklist to run before you book.
Which Peptides Should You Take? A DNA-First Decision Framework
Picking a peptide based on your goal is the wrong starting point. Your COMT, BDNF, SOD2, and GLP1R variants determine whether a protocol works before you pick the peptide.