Sample report— synthetic genetic data for demonstration only
Get Your Report — $99This report has not been evaluated by the FDA. It is for educational and informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. Not a substitute for professional medical advice. PeptidesDNA is not a medical practice, pharmacy, or healthcare provider. Consult a qualified healthcare provider before making any health-related decisions.
A look inside
Sample Report
Sample Report · What you receive
Your Genetic
Peptide Analysis
This is a sample of the full report you receive after uploading your DNA. Every section below is built from your own genetics, scored across 27 peptide compounds.
94
Markers found
of 120 targets
27
Peptides scored
compounds
94
Top match
out of 100
78%
Data coverage
26 missing
Your DNA tells a clear story.
Three genes do most of the work in shaping how your body responds to peptides — your stress chemistry, your tissue repair signal, and your methylation engine. Here is what we found, in plain language.
Balanced dopamine — sharp under pressure, but slow to come back down
COMT · rs4680 Val/Met
Upside
Faster information processing, solid working memory, strong analytical edge in calm conditions.
Watch out
Dopamine clears slowly under stress — anxiety lingers in the body longer than average. Peptides that modulate dopamine (Semax) ranked high in your report for this reason.
Reduced activity-dependent BDNF — neuroplasticity needs a push
BDNF · rs6265 Val/Met
Upside
When you do learn, it sticks. Strong consolidation, durable memory traces.
Watch out
Lower baseline BDNF means you need more deliberate stimulation — exercise, fasting, novelty — to drive new growth. Semax directly upregulates BDNF and addresses this exact gap.
Intermediate methylation — moderate folate processing
MTHFR · rs1801133 C677T (C/T)
Upside
Mid-tier folate conversion. Not the worst , not the best. Methylated B-vitamins fully restore function.
Watch out
Affects glycine and SAMe availability, both of which feed into peptide synthesis pathways. We adjusted protocol pacing to account for this.
Beyond your brain
Soft tissue
Vulnerable
COL5A1 + MMP1 variants elevate connective tissue turnover. is your single highest-confidence match for this reason.
Lactose
Tolerant
LCT rs4988235 T/T — lactase persists into adulthood. Dairy will not disrupt your gut peptide protocol.
Exercise response
Strong
ACE rs4343 G/G + favorable baseline. Your cardiovascular response to exercise is above average — zone-2 cardio will pair well with the protocol.
Significant finding
Cardiovascular9p21 region — moderate cardiovascular risk variants detected
Three variants in the 9p21 region (rs10757274, rs2383206, rs1333049) are heterozygous. This region is the single strongest population-level signal for coronary artery disease risk. Peptides that affect blood pressure or coagulation (PT-141, CJC-1295) should be approached cautiously and discussed with your physician before use.
Inflammation profile
IL6 rs1800795 G/C + TNF rs1800629 G/A — your baseline inflammatory tone runs moderately high under stress. This is the underlying reason GHK-Cu and BPC-157 ranked meaningfully above the population average in your scoring.
Anti-inflammatory peptides (GHK-Cu, KPV, Thymosin Alpha-1) will likely work harder for you than for the average user.
Vitamin D
Likely deficient
GC rs2282679 A/C — reduced vitamin D binding protein. Your serum 25(OH)D is likely 20–30% lower than your sun exposure would suggest.
Test 25(OH)D. Supplement 2,000–4,000 IU daily with K2.
Vitamin A
Slow conversion
BCMO1 rs7501331 T/T — your body converts beta-carotene to retinol about 50% less efficiently than average. Plant sources alone may not meet baseline.
Favor pre-formed retinol (animal sources or a supplement) over beta-carotene.
Sleep & Circadian
Mild evening chronotype
PER3 + CLOCK variants suggest you run as a mild night owl. Cortisol peaks roughly 90 minutes later than average. Schedule peptides accordingly.
Push the BPC-157 morning dose to 7–8 AM instead of 6. Take Semax at 9 PM, not 10.
How your methylation affects peptides
You are a moderate methylator. MTHFR C677T + MTRR rs1801394 A/G means methylation runs at about 70% of population baseline. This affects how your body processes peptides that interact with the SAMe cycle, as well as your sensitivity to specific co-factors.
Methylated B-vitamins recommended
Use methylfolate (5-MTHF) and methylcobalamin (B12) instead of folic acid and cyanocobalamin. This supports the peptide synthesis pathways your DNA partially under-resources.
Glycine demand is elevated
BPC-157 metabolism is glycine-dependent. Bone broth or 5 g of supplemental glycine daily before bed supports the protocol meaningfully.
Space high-dose niacin from peptides
Niacin above 500 mg depletes methyl groups in real time. Separate from any peptide dose by at least four hours.
Avoid during peptide protocols
Pathway scores
How your genetics score across six biological systems. Higher = stronger genetic signal for peptides targeting that pathway.
Tissue Repair
Strong
Inflammation
Elevated
Gut Integrity
Strong
GH / IGF-1 Axis
Above avg
Neuroprotection
Strong
Longevity
Above avg
Your peptide matches
Based on your profile, here's what your genetics suggest.
Each compound scored 0–100 against your genetics. Tap any peptide to see your specific markers and reasoning.
How to read the score: it measures genetic match to your DNA — not clinical value, evidence strength, or availability. A prescribable, approved drug can rank below an investigational one it out-performs, purely because genetics is the axis. Read the score alongside the tier & regulatory tags on each match.
Your Markers
COL5A1 rs12722 C/T
Elevated soft-tissue turnover
MMP1 rs1799750 1G/2G
Faster collagen breakdown
TGFB1 rs1800469 C/T
Moderate TGF-β expression
What this means for you
Recovery from joint, tendon, and ligament strain will respond meaningfully to — likely above-average effect vs. the population mean. Expect noticeable change in soft-tissue healing within three to four weeks.
Why it ranks #1
Moderate-HighThree of your strongest variants converge on connective tissue: turnover, matrix breakdown, and TGF-β signaling. directly stimulates each pathway. This is your single highest-confidence match.
Dose
400 mcg/day
Stacking
Pairs with GHK-Cu (#2) for surface + structural repair. Add TB-500 (#7) for tendons specifically.
Not approved by any regulatory agency. No completed human clinical trials. Dosing based on animal PK data and practitioner protocols.
Your Markers
TGFB1 rs1800469 C/T
Below-average TGF-β
MMP1 rs1799750 1G/2G
Elevated turnover
ELN rs2071307
Reduced elastin baseline
What this means for you
Skin tone, fine lines, post-injury scar tissue — all likely to show measurable change at 8–12 weeks. Topical use carries the strongest evidence base; injectable use is off-label.
Why it ranks #2
Highhas the strongest cosmetic and topical clinical literature of any peptide in the report. Your TGF-β + + elastin profile gives it meaningful room to work above the population mean. This is your highest tier-1 (clinical evidence) match.
Dose
2 mg/day
Stacking
Layer after BPC-157 for systemic + surface repair. Excellent companion with Vitamin C for collagen synthesis.
Used in cosmetics (topical). Not approved as a drug by any regulatory agency. Injectable use is off-label.
Your Markers
BDNF rs6265 Val/Met
Reduced activity-dependent secretion
COMT rs4680 Val/Met
Intermediate dopamine clearance
CYP2D6 *1/*4
Intermediate metabolizer
What this means for you
Sharper focus during cognitively demanding work, better stress recovery, faster mental-fatigue clearance. Likely strong effect at low doses given your .
Why it ranks #3
ModerateYour Val/Met BDNF reduces baseline activity-dependent neurotrophin release. Semax directly upregulates BDNF, addressing exactly this gap. COMT Val/Met means dopamine clearance is balanced — Semax's stimulant effect should not tip you into edge.
Standard dose
200–600 mcg/day intranasal
Your dose
200 mcg/day
50% less — CYP2D6 intermediate — start at half-dose and titrate upStacking
Cognitive stack — independent of recovery peptides. Do not combine with Selank (mechanism overlap).
Approved in Russia/Ukraine. Not FDA-approved. No regulatory approval in the US or EU.
Your Markers
FUT2 rs601338 G/A
Secretor positive (favorable)
IL6 rs1800795 G/C
Elevated inflammatory baseline
NOD2 rs2066847
Normal barrier function
What this means for you
Better absorption of every peptide in this report. Reduced systemic inflammation downstream. Start GLP-2 first — it raises the absorption baseline for the other compounds.
Why it ranks #4
Moderate-HighSecretor-positive status means your gut mucosa produces ABO antigens — favorable for microbiome diversity. Combined with your elevated IL-6 inflammatory tone, gut-barrier reinforcement (GLP-2's mechanism) addresses your strongest pathway weakness directly.
Dose
3 mg/day
Stacking
First in protocol. Improves uptake of BPC-157 and GHK-Cu when run upstream.
Teduglutide (Gattex/Revestive) is FDA/EMA-approved for short bowel syndrome. Must be prescribed by a physician.
Your Markers
GLP1R rs10305420
Favorable response variant
TCF7L2 rs7903146 C/T
Moderate diabetes risk
FTO rs9939609 T/A
Moderate satiety dysregulation
What this means for you
If pursued under physician supervision for weight or metabolic management, you fall in the cohort with predicted above-mean response. Discuss with your prescribing physician.
Why it ranks #5
HighGLP1R variant aligns with the above-average responder cohort in the Phenomix Sciences trial (Cell Metabolism, 2023). This is the single strongest pharmacogenomic prediction in your report — you carry the favorable .
Dose
Above-average responder expected
Stacking
Independent of peptide stack. Do not combine with AOD-9604 without spacing doses.
Prescription only. FDA-approved as Ozempic/Wegovy/Rybelsus. Must be prescribed by a physician.
Your Markers
FTO rs9939609 T/A
Moderate fat storage risk
PPARG rs1801282 Pro/Pro
Below-average insulin sensitivity
ADRB3 rs4994 T/T
Normal thermogenesis
What this means for you
Marginal benefit likely. Best paired with caloric deficit and zone-2 cardio, not a primary tool on its own.
Why it ranks #6
Low-ModerateYour moderate FTO + below-average PPARG profile suggests fat oxidation is your bottleneck, not satiety. AOD-9604 targets fat metabolism directly. Note: evidence is exploratory — the Phase IIb trial failed its primary endpoint.
Dose
300 mcg/day
Stacking
Pairs with cardio protocols. Do not stack with Semaglutide on the same day.
Not FDA-approved. Phase IIb trial (536 subjects, 2006-2007) failed to meet primary endpoint. Development abandoned by Metabolic Pharmaceuticals.
Your Markers
ACTN3 rs1815739 R/X
Mixed fiber type
MSTN rs1805086
Normal myostatin
COL5A1 rs12722 C/T
Elevated tendon vulnerability
What this means for you
Best as an add-on to for tendon-specific recovery, not a primary tool on its own.
Why it ranks #7
Low-ModerateYour mixed fiber type + elevated tendon vulnerability gives a clear target. Evidence is mechanistic — most data is animal, but the pathway logic is sound.
Dose
2.5 mg, 2×/week
Stacking
Classic stack with BPC-157 for joint protocols.
Not approved by any regulatory agency. Banned by WADA in competitive sports. No completed human clinical trials for therapeutic use.
Your Markers
COMT rs4680 Val/Met
Balanced dopamine clearance
BDNF rs6265 Val/Met
Reduced baseline
SLC6A4 5-HTTLPR L/L
Long allele (favorable serotonin transport)
What this means for you
Useful for acute stress events or high-pressure work sessions. Do not combine with Semax — overlapping mechanisms.
Why it ranks #8
ModerateYour COMT Val/Met under stress + long 5-HTT favors GABAergic . Selank targets GABA-A modulation specifically.
Standard dose
300–600 mcg/day intranasal
Your dose
300 mcg/day
50% less — CYP2D6 intermediate — half-dose startStacking
Standalone, acute-use only. Cycle on and off.
Approved in Russia. Not FDA-approved. No regulatory approval in the US or EU. Dosing based on Russian clinical protocols.
Your Markers
FOXO3 rs2802292 G/T
Favorable longevity variant
SOD2 rs4880 C/T
Intermediate antioxidant
TERT rs2853669
Normal telomerase regulation
What this means for you
Quarterly 10-day cycles. Do not expect short-term effects — this is a long-game compound.
Why it ranks #9
Low-ModerateYour favorable FOXO3 longevity variant complements Epithalon's telomerase activation. Evidence is from Russian laboratories (Khavinson) — no Western RCTs exist.
Dose
5 mg/day, 10-day cycle
Stacking
Independent. Quarterly cycles.
Not approved by any regulatory agency. Research primarily from Russian laboratories (Khavinson). No Western clinical trials.
Your Markers
IL6 rs1800795 G/C
Elevated baseline
TNF rs1800629 G/A
Mild pro-inflammatory tone
Not on your chip
What this means for you
Useful for viral resilience and post-illness recovery. Best in fall/winter cycles.
Why it ranks #10
Low-ModerateLimited genetic dataYour inflammatory tone gives Thymosin Alpha-1 a target. Score is held back by missing HLA-DRB1 data — with a full panel this would likely refine to roughly 75.
Dose
1.6 mg, 2×/week
Stacking
Seasonal use. Pairs naturally with Vitamin D supplementation.
Approved in 35+ countries as Zadaxin for hepatitis and immune modulation. Not FDA-approved.
2 peptides may benefit from lower starting doses.
We checked all 27 peptides against your seven CYP enzymes and your genetic profile. Two peptides need adjusted starting doses because of your intermediate CYP2D6 phenotype.
CYP2D6 intermediate — start at half-dose and titrate up
CYP2D6 intermediate — half-dose start
All other 8 peptides: standard dosing
Most peptides are broken down by peptidases, not CYP liver enzymes. Your CYP profile doesn't affect their dosing. Each peptide card above shows its specific dose.
Which combos work. Which don't.
Based on known pharmacological pathways, we flagged potential interactions between your top compounds. This is not a comprehensive interaction check — consult your healthcare provider.
Classic complementary stack — structural + surface repair. No pathway overlap or competition.
GLP-2 supports gut barrier; supports systemic tissue. Synergistic for digestive recovery.
Both target fat metabolism through different mechanisms. Can stack, but space doses by ≥4 hours and monitor blood glucose closely.
Both modulate central neurotransmitters with overlap. Risk of overstimulation. If using both, separate cycles by ≥1 month.
Canonical recovery stack. No pharmacological conflict. Frequently used together in tendon protocols.
Selank's effect may mask early hypoglycemia warning signs. Monitor glucose carefully if combining.
When you take it matters as much
as what you take.
We built a daily schedule that aligns each peptide with your body's natural rhythms.
Morning
6:30–8:30 AM (shifted later for your chronotype)
Take with first meal. Aligns with cortisol peak — tissue repair signal is highest in the morning.
Gut barrier activity is highest pre-meal. Take 20 minutes before breakfast.
Midday
12:00–1:00 PM
Lunch-break application — skin and surface tissue. Avoid direct sunlight for 30 minutes after.
Evening
6:00–7:00 PM
Twice-weekly cadence. Post-workout aligns with the repair cascade.
Night
9:00–10:00 PM (90 minutes before bed)
Half-dose for your CYP2D6. Promotes memory consolidation during sleep — do not take after 10 PM (insomnia risk).
A suggested approach, in three phases.
Establish gut + baseline repair
Start by reinforcing gut absorption and systemic tissue baseline. GLP-2 first raises uptake of everything that follows. begins addressing your turnover signature.
Where to get it
Add tissue + metabolic
Layer for surface repair and elastin support. If pursuing metabolic optimization under physician care, is predicted to respond favorably to your GLP1R variant.
Where to get it
Cognitive layer + recovery scale-up
Add the cognitive layer for sustained focus. reinforces tendon-specific repair. Re-evaluate biomarkers at week 12 before cycling.
Where to get it
5 markers weren't on your chip
23andMe was built for ancestry, not pharmacogenomics. Your report is still valuable with the 94markers we found — these missing ones would refine scores, not change the overall picture.
signaling variant — would refine and AOD-9604 scores by roughly five points either direction.
Affects: Semaglutide, AOD-9604 · rs7799039
Angiotensinogen — important for blood-pressure-pathway peptides. Not critical for your current top 10.
Affects: PT-141, blood pressure pathway · rs5051
Bone density signaling — relevant for IGF-1 axis peptides if you choose to layer those in later.
Affects: CJC-1295, Sermorelin · rs3736228
Adrenergic receptor — affects stimulant peptide response (Semax, Selank).
Affects: Semax, Selank · rs28365031
Immune typing — required for full Thymosin Alpha-1 scoring. Standard on pharmacogenomic chips but missing from 23andMe.
Affects: Thymosin Alpha-1, LL-37 · —
Caffeine sensitivity
Slow
CYP1A2 *1F/*1F variant — you clear caffeine about 30% slower than average. Keep your last coffee before noon for clean peptide nights.
Alcohol metabolism
Normal
ADH1B + ALDH2 standard variants. No flushing reaction expected. No specific interaction concern with peptide protocols.
Saturated fat sensitivity
Moderate
APOE ε3/ε3 — average lipid response to saturated fat. A Mediterranean-pattern diet pairs well with any peptide protocol.
Your liver enzymes & peptide dosing
Most peptides bypass your liver entirely — they're broken down by peptidases, not CYP enzymes. But a few peptides that affect dopamine and hormones are influenced by your CYP profile. This panel is also useful context for your doctor for any prescription medications. This should not be used to start, stop, or change any medication.
7 enzymes profiled
About 30% slower than average. Affected: Semax, Selank, oxytocin. Starting doses reduced accordingly. Tell your physician — this affects many antidepressants and opioids.
Standard clearance of , , and roughly 50% of all prescription drugs. No adjustment needed.
Faster clearance of certain compounds. Affects clopidogrel and some PPIs — not a major concern for peptide protocols, but worth mentioning to your physician.
Standard NSAID and warfarin metabolism. No concerns.
Slow caffeine clearance — keep coffee before noon to avoid sleep disruption on Semax nights.
Standard metabolism of niche substrates. No concerns.
Standard ethanol and small-molecule metabolism. No concerns.
CYP2D6 Intermediate Metabolizer (*1/*4)
You clear CYP2D6-dependent compounds about 30% slower than the population average. We adjusted Semax and Selank starting doses accordingly. Mention this to any physician prescribing antidepressants, opioids, or beta-blockers — it materially affects their pharmacology.
About this report
This is not medical advice. This report has not been evaluated by the FDA. It is for educational and informational purposes only. It is not intended to diagnose, treat, cure, or prevent any disease. It is not a substitute for professional medical advice, diagnosis, or treatment. PeptidesDNA is not a medical practice, pharmacy, or healthcare provider.
Consult your healthcare provider. Any dosage decision should be made by or in consultation with a qualified healthcare provider. Dosage ranges shown are from published research and practitioner protocols — they are not prescriptions. Do not start, stop, or change any medication based on this report.
Evidence varies. Scores reflect pathway-level inference from published research, not clinically validated diagnostic results. The strongest pharmacogenomic data exists for GLP-1 receptor agonists. For most other peptides, genetic matching is based on pathway-level inference. Most peptides discussed are not FDA-approved drugs. Availability and legal status of peptides varies by jurisdiction.
Interactions are not comprehensive. The interaction flags in this report are based on known pharmacological pathways. This is not a comprehensive drug interaction check and does not replace consultation with a pharmacist or physician regarding potential interactions with your current medications.
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