VIP

What people use VIP for

Reported uses, roughly in order of how often they are the reason someone goes looking. Whether it works for any of them is a separate question, answered under each one.

Severe lung injury

Where it has actually been trialled, as intravenous aviptadil in hospitalised patients with respiratory failure.

Inflammation

Its natural role, and the basis for most of the interest in it.

Mould illness and CIRS

The reason most people search for it, taken as a nasal spray. This use has no controlled trial behind it.

Mechanism of Action

How VIP works

VIP dosage calculator

Opens at 50 mcg, from the doses reported for VIP. Change any box to match your own vial. It works out where to pull the plunger to.

Full reconstitution chart and worked examples.

VIP side effects: what people reported

VIP widens blood vessels, which is where nearly everything people report comes from. Most of it shows up in the first few doses and settles as the body adjusts.

Dose matters. Blood-pressure effects track the dose, which is why protocols start very low.

Source: Reported use, largely nasal, plus the pharmacology of the peptide. This is a summary of published findings, not a complete safety profile and not medical advice. VIP should only be considered with a qualified clinician who knows your history.

The dots after each gene are where your own result goes. Your report fills them in with the two letters you carry at that position.

Commonly combined with

What VIP is most often paired with, and why:

KPV

Anti-inflammatory StackEmerging Evidence

KPV (Lys-Pro-Val)

A three-amino-acid fragment snipped off the end of a hormone your body already makes. Almost every page describes it as switching on a melanocortin receptor; the research fairly clearly says it does not. What it appears to do instead is more interesting, and it is why nearly all the good data is about the gut rather than skin.

4

Gene variants

15+

Studies

Thymosin Alpha-1 (Immune Stack)

Sourcing & access

Where to buy VIP

VIP is sold as a research compound, not a licensed medicine, so quality and legal status vary widely by country and vendor. If you're sourcing it, treat independent purity testing as non-negotiable.

• Insist on a recent third-party Certificate of Analysis (COA) for the exact batch — labs like Janoshik verify purity and identity.
• Check the legal status where you live before ordering — it differs from country to country.
• Reconstitute correctly with bacteriostatic water and start at a conservative dose.

Educational information only, not medical advice. Some outbound links are affiliate links (disclosed, at no extra cost to you). Most peptides are not FDA-approved — consult a qualified professional and check your local laws before purchasing.

Worth knowing before you consider VIP

Interactions and situations where there is a specific reason to be careful. Where the honest answer is that nobody has studied something, it says so and says what that leaves open.

The trialled use and the sold use are not the same

Intravenous aviptadil in an intensive care unit and a nasal spray bought online for mould illness share a molecule and nothing else. Route, dose, setting and monitoring all differ, and results from one say nothing about the other.

It widens blood vessels, so blood pressure can drop

This is its core action rather than a side effect. In hospital use it is given with monitoring for exactly that reason. Flushing and a fall in blood pressure are the expected effects of a vasodilator.

It breaks down very quickly

Natural VIP has a half-life of a couple of minutes in blood, which is the central practical problem with using it as a drug and the reason hospital use is by continuous infusion rather than a single dose.

Frequently Asked Questions