Battle Of The Lipolytic Peptides | Growth Hormone Vs. HGH-Frag 176-191 Vs. AOD-9604
A bodybuilding creator shares his own experience comparing HGH Frag 176-191, AOD-9604 and growth hormone for fat loss, covering his dosing, timing, bloodwork and verdict.
Key moments
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- 0:22Setting up the three-way comparisonSteve says he will compare HGH Frag, AOD-9604 and pharmaceutical grade growth hormone using his own experience, and he expects growth hormone to win on fat loss.
- 1:56What the fragments areHe describes HGH Frag 176-191 as the last 16 amino acids of growth hormone and AOD-9604 as the same stretch with a tyrosine substitution.
- 3:25No difference between the twoHe reports similar fat loss from 250 micrograms of each, with no change in his blood work when dosed 30 minutes before a draw.
- 5:41His dosing and timing protocolHe explains taking 250 micrograms before cardio or training, then shifting to dosing just before the gym and walking between sets.
- 11:41Molecular weight comparisonHe works out that 250 micrograms of the fragment matches the sequence content of about 9.32 IU of growth hormone, and says the lipolytic effect is not close.
- 15:59Fat loss versus growth hormoneHe estimates 250 micrograms of either fragment equals about 1 IU of growth hormone, and says 500 micrograms gave him no extra benefit.
- 19:22Final verdict and who it suitsHe says growth hormone is superior if you can afford it and want more than fat loss, while the fragments suit fat loss alone without water retention or lethargy.
- 23:02Closing thoughts and resultsHe shows his current physique, says he is open about what he uses, and says he may keep using the fragments.
What the video says
VigorousSteve compares HGH Frag 176-191, AOD-9604 and growth hormone as fat loss tools, drawing only on his own experience and that of some clients. He says he ran roughly 3 to 4 months of HGH Frag, mixed in AOD-9604 here and there, and had stopped injecting growth hormone about six months earlier. He describes both fragments as the last 16 amino acids of growth hormone, the part said to carry its lipolytic effect. AOD-9604 swaps in a tyrosine, which he says the peptide community believes makes it more potent and longer lasting. He says he did not notice any difference between 250 micrograms of one and 250 micrograms of the other.
He says his protocol began with 250 micrograms about an hour before fasted cardio or a workout, up to seven times a week. He later decided the effect is short lived and works better if he injects 5 to 10 minutes before training and walks between sets. In his account, fat loss was clearly noticeable the next day when he did both, and much less when he rested between sets. He rates the fragments at two and a half to three stars, well below the five stars he gives 5 Amino 1MQ. He also reports that injecting 30 minutes before a blood draw did not change his triglycerides or glucose, unlike growth hormone, and he calls the missing triglyceride rise a red flag. Doubling to 500 micrograms gave him no extra fat loss.
He then compares the fragment with growth hormone by molecular weight. He puts the fragment at 8.13% of the most common growth hormone isoform and calculates that 250 micrograms matches the sequence content of about 9.32 IU of growth hormone, while saying the fat loss is nowhere near comparable. From experience he equates 250 micrograms to roughly 1 IU of growth hormone, and says fasted dosing seems to work better.
His verdict is that growth hormone is superior if cost is no issue and you want more than fat loss, since it brings recovery, sleep, hair and nail effects that the fragments lack. If the goal is only fat loss without water retention, daytime lethargy or a moon face, he says HGH Frag or AOD-9604 wins, and he may keep using them.
On each compound
AOD-96043:05
Steve says AOD-9604 is the growth hormone fragment with a tyrosine swap that the peptide community calls more potent. He saw no difference from HGH Frag at 250 micrograms and rates both two and a half to three stars for fat loss.
See how your DNA reads AOD-9604What this video doesn’t settle
- It is one person's experience, with no control group, blinding or placebo comparison.
- Fat loss is judged by feel and pinching, and diet, cardio, walking between sets and 5 Amino 1MQ all overlapped, so the fragments' own effect is unclear.
- The equivalence of 250 micrograms to about 1 IU of growth hormone is his own estimate, and his molecular weight calculation is described by him as dubious.
Questions this video answers
Is AOD-9604 more potent than HGH Frag 176-191?
Steve says the peptide community claims the tyrosine change makes AOD-9604 more potent and longer lasting. From his own use and some clients, he found the two interchangeable, though he allows that AOD-9604 might be slightly better.
What dose of HGH Frag or AOD-9604 does Steve use?
He describes 250 micrograms as his effective dose, taken directly before activity. Doubling to 500 micrograms did not add fat loss for him, and he says dosing while fasting seemed to work better.
How does HGH Frag compare to growth hormone for fat loss?
Steve estimates 250 micrograms of either fragment is about 1 IU of growth hormone for fat loss. He says higher growth hormone doses gave him more fat loss, along with recovery, sleep and cosmetic effects the fragments lack.
Did HGH Frag affect Steve's blood sugar or triglycerides?
He says injecting 250 micrograms 30 minutes before a blood draw did not change his serum triglycerides or glucose, whereas growth hormone does. He calls the lack of a triglyceride rise a small red flag.
Why would someone choose a fragment over growth hormone, according to Steve?
He says the fragments cause no water retention or daytime lethargy and avoid the moon face he gets on 2 units of growth hormone. He adds that they are cheaper and suit someone after fat loss only.
Video by VigorousSteve on YouTube, embedded as published. The summary is written by PeptidesDNA from the video; every claim in it is the speaker’s. Not affiliated with or endorsed by the creator. Not medical advice.
