Dr. Admits - I Was WRONG AGAIN About GHK-Cu
A 9-minute solo explainer in which Dr. Ashley Froese lays out her case for GHK copper beyond skincare, with her notes on copper balance, delivery methods and safety concerns.
With Dr. Ashley Froese (Doctor (degree not specified))
Key moments
Tap a moment to play the video from there.
- 0:00Why she changed her mindFroese says she wrongly saw GHK copper as a topical-only product and previews the topics: aging repair, safety, and the FDA review.
- 0:41What GHK copper isShe says the body makes GHK as a three amino acid byproduct of collagen breakdown, and that it binds copper strongly, taking it from albumin.
- 2:01Decline with ageFroese says GHK in the blood is about 60% lower by age 60, and argues stiffened collagen traps it, so less copper reaches repair sites.
- 3:34Gene expression claimsShe says GHK influences over 4,000 genes, turning up repair and antioxidant genes and turning down inflammatory ones, with effects lasting longer than the molecule.
- 4:43Research she citesShe lists a human topical skin study, preclinical wound healing work, cellular DNA repair studies, hair follicle research, and the FDA's interest in COPD and emphysema.
- 6:23Copper and zinc balanceFroese lists signs she links to copper depletion and says zinc and copper can deplete each other. She says some serious users take 15 to 30 mg of zinc.
- 7:22Topical, inhaled, injectedShe says it can be used in creams and serums because it is small, wonders aloud about inhaling it, and says injection is the route the FDA is reviewing.
- 8:09Why injections stingShe gives two reasons for stinging: the acidic pH that keeps it stable in the vial, and a brief inflammatory response to copper entering the skin.
- 8:41Safety concerns and wrap-upShe names copper overload, zinc deficiency and the angiogenesis question as the main concerns, and says nobody knows whether the tumor worry is valid.
What the video says
Dr. Ashley Froese opens by saying she was wrong to think GHK copper was only useful on the skin. She says she was not looking at the right research. She frames the video as an explanation of what happens to the body's repair system with age, where GHK copper might fit, and what the risks are.
She describes GHK as a three amino acid fragment the body makes when old type 1 collagen and a collagen-bound protein called SPARC are broken down during remodeling or wound repair. According to her, it quickly binds copper, even pulling it off albumin, and the resulting complex acts as a signal. She says blood levels of GHK are about 60% lower by age 60, and argues that stiffer, glued-together collagen traps GHK so less copper reaches repair sites.
Froese says the complex delivers copper to enzymes involved in antioxidant defense and collagen and elastin cross-linking, and supports new blood vessel growth. She also says the GHK peptide itself changes gene expression, citing over 4,000 human genes, and that these changes last days even though the molecule's half-life in blood is about 30 minutes to an hour. For evidence she mentions a human topical study on skin density and thickness, preclinical wound healing studies, cellular DNA repair work, hair follicle research, and early findings on sirtuin activation and IL-6. She says the FDA is re-evaluating injectable GHK copper for several uses, including COPD and emphysema.
The last third covers practical points. She lists signs she associates with low copper, explains how zinc and copper can deplete each other, and says some heavy users take 15 to 30 mg of zinc alongside it, while stressing this is not medical advice. She notes topical use is allowed, explains why injections sting, and names copper overload, zinc deficiency and the unresolved question of new blood vessel growth feeding a tumor as the main safety concerns. She also says she uses a serum on her own hairline, and that serum link is promoted in the description.
On each compound
GHK-Cu0:00
Froese presents GHK copper as a naturally made repair signal that declines with age, and as more than a skin peptide. She cites human topical, preclinical and cellular research, describes a possible FDA re-evaluation of the injectable form, and flags copper overload, zinc depletion and angiogenesis as concerns.
See how your DNA reads GHK-Cu“I am just a doctor on YouTube. I am not your doctor.”
What this video doesn’t settle
- The video gives no citations, so the human skin study, the 4,000 gene figure and the sirtuin and IL-6 findings cannot be checked from what is said.
- Most of the evidence she describes is preclinical or cellular, and she names only one human study, a topical one, so benefits of injected GHK copper are not established here.
- The FDA re-evaluation is stated without a source, and the video does not explain what the review's outcome would mean.
Questions this video answers
What is GHK copper according to Dr. Ashley Froese?
She describes GHK as a three amino acid fragment released when type 1 collagen and the SPARC protein are broken down. It binds copper and, in her words, acts as a signal that influences repair and gene expression.
What safety concerns does Froese raise about GHK copper?
She names copper overload, zinc deficiency from long-term high-dose use, and the question of whether promoting new blood vessels could feed a tumor. She says she does not know whether that last concern is valid and that nobody does.
Why does injectable GHK copper sting?
Froese gives two reasons. The vial is kept at an acidic pH for stability, which can irritate nerve endings in neutral tissue, and the local rush of copper can cause a brief inflammatory response.
What does Froese say about GHK copper and zinc?
She says high zinc intake can block copper absorption, and that long-term high-dose copper, including GHK copper, can deplete zinc. She notes that some serious users take 15 to 30 mg of zinc, and calls this an observation rather than medical advice.
What is the FDA doing with GHK copper, per this video?
Froese says the FDA is removing injectable GHK copper from its do-not-compound list and re-evaluating it for wound repair, dermal atrophy, COPD and lung remodeling, and hair follicle restoration. This is her account, and the video gives no source or date for it.
Video by This Is Not Covered - Dr. Ashley Froese on YouTube, embedded as published. The summary is written by PeptidesDNA from the video; every claim in it is the speaker’s. Not affiliated with or endorsed by the creator. Not medical advice.
