The Only Peptide that Builds Collagen, Muscle, and Hair (longevity peptide)

Thomas DeLauerEducator, Nutrition and performance14 minSep 2025342K views

Thomas DeLauer reviews early, mostly preclinical research on GHK-Cu for cognition, oxidative stress, collagen, wound repair, blood vessels, and hair, and shares his own experience.

Key moments

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  1. 0:00Why GHK-Cu and the caveatDeLauer lists the areas where he says GHK copper peptide looks promising and warns that most of the research is preclinical.
  2. 1:59What GHK-Cu isHe describes it as a naturally occurring tripeptide that binds copper and says its levels drop from about 200 to about 80 nanograms per milliliter between ages 20 and 60.
  3. 2:40Cognitive findingsHe describes a preclinical sleep deprivation study where treated animals had less impairment and less hippocampal inflammation.
  4. 4:10Oxidative stress and inflammationHe cites lung studies reporting lower TNF and IL6 and higher glutathione and superoxide dismutase.
  5. 5:41Collagen and wound repairHe covers a wound study, gene expression for collagen and elastin, and a topical study with hyaluronic acid.
  6. 8:41Angiogenesis and the SPARC linkHe compares its blood vessel effects to BPC-157 and TB500 and explains that injury triggers release of GHK.
  7. 10:38DeLauer's own experienceHe says he used it for shoulder and back injuries and noticed fast body hair regrowth.
  8. 11:47Hair and skin researchHe describes preclinical hair follicle results and in vitro keratinocyte and stem cell marker findings.
  9. 13:28Comparison with BPC-157 and TB500He says GHK-Cu may suit a longer-term approach while the other two may act faster for injuries, and that a doctor should be involved.

What the video says

Thomas DeLauer, a YouTube creator who says he is not a doctor, goes through the literature on GHK-Cu, a copper-binding tripeptide he describes as naturally occurring in the body. He presents it as a longevity candidate that was first examined for tissue repair. He says early that most of the research is preclinical and that human data is lacking, so the findings should be taken with caution.

DeLauer says natural GHK levels fall with age, from about 200 nanograms per milliliter at 20 to about 80 by 60. He then cites a preclinical sleep deprivation study in which treated animals showed less cognitive impairment, less hippocampal inflammation, and an oxidative stress marker that was 11 and 14 percent lower. He also describes preclinical lung studies in which GHK-Cu was linked to lower inflammatory markers (TNF and IL6) and higher glutathione and superoxide dismutase.

The longest section covers tissue repair. DeLauer describes a wound study reporting faster healing, more collagen, and more connective tissue. He also cites an in vitro study in which GHK-Cu raised collagen and elastin gene expression, and a topical study pairing it with hyaluronic acid that increased several collagen types. On blood vessel formation, he says it works similarly to BPC-157 and TB500 but may be more stable and need a smaller dose. He adds that injury prompts the body to release GHK.

DeLauer says he used GHK-Cu for a shoulder injury and a back injury, and that his shaved body hair regrew unusually fast. He ties this to preclinical and in vitro work on thicker follicles, keratinocyte growth, and stem cell markers around follicles. He closes by saying the literature suggests it is fairly safe and could be good value. He thinks BPC-157 may suit a quick injury push, TB500 is more accelerated, and GHK-Cu may fit a longer-term approach a doctor could run. He gives no specific dose.

On each compound

GHK-Cu0:00

DeLauer calls GHK copper peptide a promising longevity candidate, citing mostly preclinical and in vitro work on cognition, oxidative stress, collagen, wound repair, blood vessels, and hair. He says human data is lacking and describes his own use for injuries.

See how your DNA reads GHK-Cu

BPC-1578:41

DeLauer mentions BPC-157 as a popular injury repair peptide known for blood vessel formation. He suggests it may be a stronger short-term option than GHK-Cu.

See how your DNA reads BPC-157

TB-50013:28

DeLauer describes TB500 as more accelerated than BPC-157 for tissue repair and says combining the two is good for injury. He contrasts both with GHK-Cu as a longer-term choice.

See how your DNA reads TB-500

“the human data is lacking”

What this video doesn’t settle

  • Nearly all the cited studies are preclinical or in vitro, so the video does not show these effects in people.
  • DeLauer's hair regrowth observation is one person's experience with no control group and no measurement.
  • He calls the peptide fairly safe based on the literature but cites no specific safety data.

Questions this video answers

What does Thomas DeLauer say GHK-Cu does?

He says the literature points to possible effects on cognition, oxidative stress, inflammation, collagen formation, wound repair, blood vessel growth, and hair follicles. He stresses that this evidence is early and mostly preclinical.

Is there human research on GHK-Cu according to this video?

DeLauer says the human data is lacking and that most studies are preclinical. The human-relevant items he cites are in vitro cell work and a topical skin study with hyaluronic acid.

How does DeLauer compare GHK-Cu with BPC-157 and TB500?

He says GHK-Cu works in a similar way for blood vessel formation but may be more stable and need less dose. He thinks BPC-157 and TB500 may be stronger and faster for injuries, while GHK-Cu may suit a longer-term approach.

What was DeLauer's personal experience with GHK-Cu?

He says he used it for a shoulder injury and a back injury and then saw shaved body hair regrow very fast, with some ingrown hairs. He links this to stem cell effects around follicles.

Video by Thomas DeLauer on YouTube, embedded as published. The summary is written by PeptidesDNA from the video; every claim in it is the speaker’s. Not affiliated with or endorsed by the creator. Not medical advice.

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