Taking The BPC-157 & TB-500 WOLVERINE STACK | Thomas Delauer

Matt KaeberleinResearcher, PhD, biology of ageing8 minMar 2025291K views

A short interview clip where Thomas Delauer describes his basic supplement routine, then his own cautious experience with BPC-157, TB-500 and growth hormone secretagogues.

With Thomas Delauer

Key moments

Tap a moment to play the video from there.

  1. 0:00Creatine dose and water retentionDelauer says 10 to 15 grams of creatine works for him where 5 grams does not, and ties this to eating few carbohydrates.
  2. 1:32TMG, magnesium and other staplesHe names TMG and magnesium as part of his basics and says peptides are only extra levers he experiments with.
  3. 2:35Anecdote versus evidenceThe host asks how to handle peptide hype given the thin evidence. Delauer calls the field largely anecdotal and fast-spreading.
  4. 3:06Why he accepts the riskHe says long-standing preclinical literature on BPC-157 and TB-500 makes the risk and reward acceptable to him. He also mentions having scans done.
  5. 3:37Angiogenesis concern and MRIBoth speakers say a full body MRI is worth considering before starting, because a peptide linked to angiogenesis could exacerbate an existing growth.
  6. 4:09Short BPC-157 cyclesDelauer says he does a couple of rounds a year in 3 to 5 week sprints, only as needed. He also says he has tried several growth hormone secretagogues.
  7. 4:41Tesamorelin side effectsHe says tesamorelin made his blood sugar behave oddly, caused flushing and disturbed his sleep, so he stopped. He says a CJC-based option helped his sleep.
  8. 5:11There is always a catchHe explains why he is skeptical of anything that triggers a growth hormone pulse, saying nothing comes for free.
  9. 5:42Current round and recoveryDelauer says his recovery and training turnaround have been the best in 10 years during his current round, and wonders if better sleep is the cause.
  10. 7:15Hype and demonizationThe host says peptides and growth hormone can be unfairly demonized as well as overhyped. Human trial data is unlikely soon, so people must weigh risk and reward with a good doctor.

What the video says

This is an 8 minute clip from an Optispan conversation. An unnamed host asks Thomas Delauer about his supplement routine, then moves to peptides. The first two minutes are about non-peptide staples, and the rest is about how Delauer approaches peptides.

On supplements, Delauer says his routine is basic: whey protein, creatine, TMG (trimethylglycine) and magnesium. He says he gets the most from 10 to 15 grams of creatine rather than 5 grams, and he links that to eating relatively few carbohydrates. He describes peptides as a place to try small extra levers for performance, not as a foundation.

On peptides, Delauer calls the field largely anecdotal and fast-spreading. He says he takes BPC-157 and TB-500 because preclinical literature has existed for a long time, which makes the risk and reward acceptable to him. He says he has had body scans done to check for tumors before using them, and that he would not have started otherwise. His stated reason is that BPC-157 is linked to angiogenesis, so anything already growing could be made worse. He recommends a full body MRI, if affordable, before starting growth hormone analogues. He describes using BPC-157 for a couple of rounds a year, in 3 to 5 week sprints, only as needed.

He then covers growth hormone secretagogues. He says he tried tesamorelin, which he felt affected his blood sugar and sleep, and he describes flushing as a known side effect. He says a CJC-based combination helped his sleep and, in a round he was finishing, his recovery and training turnaround. He also questions whether those effects come from growth hormone itself or from better sleep. He says he is wary of long-term use because there is always a catch.

The host adds that growth hormone and peptides are sometimes demonized without strong data, just as some molecules are hyped without it. The host also says human trial data is unlikely soon, so people have to weigh risk and reward with a good doctor. The clip is brief and anecdotal. It gives no doses for the peptides and no study citations.

On each compound

BPC-1573:06

Delauer says he uses it because preclinical literature exists. He does a couple of rounds a year in 3 to 5 week sprints, as needed. He says he had scans first because of its link to angiogenesis.

See how your DNA reads BPC-157

TB-5003:06

Delauer groups it with BPC-157 as a peptide with long-standing preclinical literature, which he says makes the safety profile probably fine for him. No separate details are given.

See how your DNA reads TB-500

Tesamorelin4:09

Delauer says he tried it, but it made his blood sugar do odd things and affected his sleep. He mentions flushing as a known side effect and stopped using it.

See how your DNA reads Tesamorelin

CJC-12954:09

Delauer says CJC helped his sleep. He says he is finishing a round of it, and that his recovery and training turnaround have been better than in 10 years. He notes this is anecdotal.

See how your DNA reads CJC-1295

Ipamorelin5:42

The captions suggest Delauer is finishing a round of CJC paired with ipamorelin. The name is garbled in the captions, so this pairing is inferred. He credits the round for better recovery and sleep, anecdotally.

See how your DNA reads Ipamorelin

“there's always got to be a little bit of a catch”

Matt Kaeberlein 5:11

What this video doesn’t settle

  • Everything about BPC-157, TB-500 and the growth hormone peptides is one person's experience, with no control group or measured outcomes.
  • The safety reasoning rests on preclinical studies that are not named or described, and no human trial data is cited.
  • No doses, products, sources or cycle protocols are given for any peptide, and the captions garble some compound names.

Questions this video answers

What does Thomas Delauer say about BPC-157 safety?

Delauer says preclinical literature has existed for a long time, so he judges the safety profile as probably fine. He says it is not designed for long-term use, so he does 3 to 5 week sprints a couple of times a year. He also says he got scans first because of its link to angiogenesis.

Should you get a scan before taking peptides, according to Delauer?

Delauer says that if resources allow, he would recommend a full body MRI before starting something like growth hormone analogues. He says that if something were growing, BPC-157 could exacerbate it. He says he would not have started without checking.

What side effects did Delauer report from tesamorelin?

He says tesamorelin made his blood sugar do odd things and affected his sleep, and he mentions flushing as a known side effect. He did not use a glucose monitor, so he says he could just tell. He stopped taking it.

How much creatine does Delauer take?

He says he benefits most from 10 to 15 grams, since 5 grams mostly gave him water retention. He links this to his low-carbohydrate diet and larger muscle mass. This is his personal experience.

Why is Delauer cautious about growth hormone boosting peptides?

He says nothing in life comes for free and he wants to know the catch. He says the long-term effects of growth hormone releasing peptides are unknown, so he avoids using them for long periods.

Video by Optispan on YouTube, embedded as published. The summary is written by PeptidesDNA from the video; every claim in it is the speaker’s. Not affiliated with or endorsed by the creator. Not medical advice.

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